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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLNS1A
All Species:
1.82
Human Site:
S102
Identified Species:
2.86
UniProt:
P54105
Number Species:
14
Phosphosite Substitution
Charge Score:
0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54105
NP_001284.1
237
26215
S102
A
D
E
E
E
E
D
S
D
D
D
V
E
P
I
Chimpanzee
Pan troglodytes
XP_001175048
222
24569
V94
E
E
E
S
K
E
P
V
A
D
E
E
E
E
D
Rhesus Macaque
Macaca mulatta
XP_001088333
203
22330
G75
R
D
R
S
D
C
L
G
E
H
L
Y
V
M
V
Dog
Lupus familis
XP_535567
226
24585
I98
S
G
D
D
V
E
P
I
A
E
F
R
F
V
P
Cat
Felis silvestris
Mouse
Mus musculus
Q61189
236
26003
N102
S
D
E
D
E
E
D
N
D
D
I
E
P
I
S
Rat
Rattus norvegicus
Q04753
236
26074
N102
S
D
E
D
E
D
D
N
D
D
V
E
P
I
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519221
278
30242
E110
R
D
Q
S
D
E
D
E
D
E
E
A
E
P
I
Chicken
Gallus gallus
XP_423253
238
26615
E100
P
V
A
E
G
E
E
E
D
S
D
D
D
V
E
Frog
Xenopus laevis
P54106
241
26428
E100
H
M
A
D
Q
E
E
E
E
S
E
D
D
D
D
Zebra Danio
Brachydanio rerio
NP_571499
249
27316
E100
L
E
K
D
P
D
E
E
D
E
N
E
E
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611237
215
23724
Y87
K
V
E
W
N
G
V
Y
G
D
P
P
Q
Q
A
Honey Bee
Apis mellifera
XP_624081
207
23224
I79
H
P
R
Q
C
L
Y
I
M
V
D
A
K
V
D
Nematode Worm
Caenorhab. elegans
NP_001021287
205
22895
I77
S
V
F
P
S
E
H
I
F
V
M
V
D
Q
R
Sea Urchin
Strong. purpuratus
XP_001194575
165
18108
Y37
S
F
P
H
E
C
L
Y
L
M
I
D
S
D
V
Poplar Tree
Populus trichocarpa
XP_002318279
231
25740
E102
Y
T
Q
I
E
T
G
E
D
E
D
E
S
E
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.2
85.6
82.2
N.A.
90.3
90.3
N.A.
40.6
82.3
72.1
68.2
N.A.
20.2
40
29.9
24.4
Protein Similarity:
100
93.2
85.6
85.2
N.A.
94.9
94.9
N.A.
53.2
90.3
82.5
80.3
N.A.
37.5
56.5
45.5
40.9
P-Site Identity:
100
26.6
6.6
6.6
N.A.
46.6
40
N.A.
46.6
26.6
6.6
13.3
N.A.
13.3
6.6
13.3
6.6
P-Site Similarity:
100
46.6
26.6
33.3
N.A.
66.6
66.6
N.A.
73.3
40
46.6
60
N.A.
20
20
26.6
20
Percent
Protein Identity:
25.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
48.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
14
0
0
0
0
0
14
0
0
14
0
0
7
% A
% Cys:
0
0
0
0
7
14
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
34
7
34
14
14
27
0
47
34
27
20
20
20
20
% D
% Glu:
7
14
34
14
34
54
20
34
14
27
20
34
27
14
7
% E
% Phe:
0
7
7
0
0
0
0
0
7
0
7
0
7
0
0
% F
% Gly:
0
7
0
0
7
7
7
7
7
0
0
0
0
0
7
% G
% His:
14
0
0
7
0
0
7
0
0
7
0
0
0
0
0
% H
% Ile:
0
0
0
7
0
0
0
20
0
0
14
0
0
14
14
% I
% Lys:
7
0
7
0
7
0
0
0
0
0
0
0
7
0
0
% K
% Leu:
7
0
0
0
0
7
14
0
7
0
7
0
0
0
0
% L
% Met:
0
7
0
0
0
0
0
0
7
7
7
0
0
7
0
% M
% Asn:
0
0
0
0
7
0
0
14
0
0
7
0
0
0
0
% N
% Pro:
7
7
7
7
7
0
14
0
0
0
7
7
14
14
7
% P
% Gln:
0
0
14
7
7
0
0
0
0
0
0
0
7
14
0
% Q
% Arg:
14
0
14
0
0
0
0
0
0
0
0
7
0
0
7
% R
% Ser:
34
0
0
20
7
0
0
7
0
14
0
0
14
0
20
% S
% Thr:
0
7
0
0
0
7
0
0
0
0
0
0
0
0
0
% T
% Val:
0
20
0
0
7
0
7
7
0
14
7
14
7
20
14
% V
% Trp:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
7
14
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _